Indication:
SONIB Tablet, containing Sorafenib Tosylate (INN) at a concentration of 200mg, is prescribed for treating various cancers, including hepatocellular carcinoma (liver cancer), renal cell carcinoma (kidney cancer), and differentiated thyroid carcinoma (thyroid cancer).

Pharmacology:
Sorafenib Tosylate functions as a multi-kinase inhibitor, targeting pivotal pathways implicated in tumor growth and advancement. It suppresses several kinases, including those responsible for angiogenesis and proliferation of tumor cells, ultimately leading to inhibition of cancer cell proliferation.

Dosage and Administration:
SONIB Tablet is typically administered orally, with or without food, as instructed by a healthcare professional. The specific dosage and treatment duration vary based on the cancer type, its stage, and individual patient characteristics.

Interaction:
SONIB Tablet may interact with various medications, including other anti-cancer drugs and medications metabolized by cytochrome P450 enzymes. Patients should disclose all medications, supplements, and herbal products to their healthcare provider to avoid potential interactions.

Side Effects:
Common side effects of SONIB Tablet may include diarrhea, fatigue, hand-foot skin reaction, hypertension, and rash. Serious adverse effects such as liver problems, bleeding, and heart issues may also arise. Patients should promptly seek medical attention if they experience severe or persistent side effects.

Precautions and Warnings:
Close monitoring is essential for patients receiving SONIB Tablet treatment, especially regarding liver function tests and blood pressure. Use of SONIB Tablet during pregnancy may result in fetal harm, necessitating contraception for both genders during treatment and for a specified period afterward. Breastfeeding is not recommended while taking SONIB Tablet.

Overdose Effects:
In instances of SONIB Tablet overdose, patients may experience intensified adverse effects, including diarrhea, rash, and liver toxicity. Management typically involves supportive care and close monitoring for complications. Immediate medical attention is advised if overdose is suspected.