Indication:
CERINIB, containing Ceritinib in 150 mg capsules, is prescribed for treating specific cancer types, particularly non-small cell lung cancer (NSCLC) characterized by specific mutations in the anaplastic lymphoma kinase (ALK) gene.

Pharmacology:
Ceritinib, functioning as a tyrosine kinase inhibitor, selectively targets and impedes the activity of the ALK protein, which plays a role in the growth and spread of cancer cells. Ceritinib’s mechanism involves blocking ALK, thereby curbing tumor growth and advancement.

Dosage and Administration:
The recommended dosage of CERINIB is typically administered orally once daily, with or without food. Dosing specifics may differ based on individual patient characteristics and healthcare provider directives.

Interaction:
CERINIB has the potential to interact with various medications, including strong CYP3A inhibitors and inducers, which may influence its metabolism and effectiveness. Patients should disclose all medications, supplements, and herbal products to their healthcare provider to prevent potential interactions.

Side Effects:
Typical side effects associated with CERINIB may include gastrointestinal issues (e.g., nausea, vomiting, diarrhea), fatigue, elevated liver enzymes, and electrolyte level fluctuations. Additionally, respiratory symptoms like cough or shortness of breath may occur. Serious adverse effects such as severe diarrhea, liver complications, and pulmonary issues are also possible.

Precautions and Warnings:
Close monitoring is essential for patients undergoing CERINIB therapy, particularly for gastrointestinal, hepatic, and pulmonary adverse reactions. Regular liver function tests are advisable during treatment. CERINIB usage during pregnancy may pose a risk of fetal harm, necessitating contraception for both sexes during treatment and for a post-treatment period. Breastfeeding is discouraged while taking CERINIB.

Overdose Effects:
In cases of CERINIB overdose, patients may experience intensified adverse effects such as gastrointestinal symptoms or liver toxicity. Overdose management typically involves supportive care and monitoring for complications. Prompt medical attention is advised if an overdose is suspected.