Rulicent 10 mg Tablets – Ruxolitinib (Incepta)

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Feature Details
Brand Rulicent
Generic Ruxolitinib
Strength 10 mg
Manufacturer Incepta Pharmaceuticals
Form Tablet
Use Vitiligo, Atopic dermatitis, Myelofibrosis
Pack 10 tablets
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What is Rulicent 10 mg?

Rulicent 10 mg Tablet is a Ruxolitinib-based JAK1/JAK2 inhibitor manufactured by Incepta Pharmaceuticals.
It is widely prescribed for skin conditions like vitiligo and eczema, as well as hematologic disorders including myelofibrosis and polycythemia vera.

Ruxolitinib works by blocking the Janus Kinase (JAK) pathway, which decreases inflammation and abnormal immune activity. As a result, it helps restore skin pigmentation and improves symptoms of chronic inflammatory and blood disorders.


Key Benefits of Rulicent 10 mg

  • ✔ Effective in non-segmental vitiligo repigmentation

  • ✔ Reduces inflammation in atopic dermatitis (eczema)

  • ✔ Controls excessive immune response

  • ✔ Treats myelofibrosis by reducing spleen size and symptoms

  • ✔ Helps manage polycythemia vera when other treatments fail

  • ✔ Quality-assured product from Incepta Pharmaceuticals


Uses of Rulicent 10 mg Tablets

🔹 Dermatology

  • Vitiligo (NSV) – promotes melanin restoration

  • Atopic Dermatitis (Eczema) – reduces itch, redness & flare-ups

🔹 Hematology (Blood Disorders)

  • Myelofibrosis

  • Polycythemia Vera (PV)

  • Graft-versus-host disease (GVHD)

  • Other myeloproliferative neoplasms (MPN)


How Rulicent 10 mg Works

Ruxolitinib blocks the JAK-STAT signaling pathway, which:

  • Stops overactive immune cells

  • Decreases cytokine production

  • Reduces skin inflammation

  • Controls abnormal bone marrow cell growth

  • Improves skin repigmentation

This dual dermatology + hematology action makes it a highly effective modern therapy.


Dosage

Dose depends on the condition and patient profile:

  • Vitiligo / Eczema: As prescribed by dermatologist

  • Blood Disorders: Usually 10–20 mg twice daily depending on platelet count

Never self-medicate. Always follow doctor’s instructions.


Side Effects

Common side effects (dose-dependent):

  • Headache

  • Dizziness

  • Rashes

  • Low blood cell count (rare)

  • Increased infection risk


Storage

Store at temperature below 25°C, away from direct sunlight and moisture.

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