Selinexor 20 mg Tablet for multiple myeloma treatment

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Selinexor 20 mg Tablet (Selinex) is a targeted oncology medicine used in the treatment of multiple myeloma and diffuse large B-cell lymphoma. It works by inhibiting nuclear export proteins, leading to cancer cell death. Prescription use only.

Field Details
Brand Name Selinex
Generic Name Selinexor
Strength 20 mg
Pack Size 16 Tablets
Dosage Form Tablet (Oral)
Manufacturer Everest Pharmaceuticals Ltd.
Made in Bangladesh
Reference Brands Xpovio, Nexpovio
Drug Class Selective Inhibitor of Nuclear Export (SINE)
Primary Category Oncology Medicines
Secondary Category Multiple Myeloma Treatment
Therapeutic Category Targeted Cancer Therapy
Indication Multiple Myeloma, Diffuse Large B-Cell Lymphoma (DLBCL)
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What is Selinex (Selinexor 20 mg Tablet)?

Selinex is an oral anti-cancer medicine containing Selinexor, used in the treatment of certain blood cancers. It belongs to the class of Selective Inhibitors of Nuclear Export (SINE) and works by blocking exportin-1 (XPO1), a protein that helps cancer cells survive.

Selinex is indicated for patients with advanced or relapsed malignancies under specialist supervision.


Uses of Selinex (Selinexor 20 mg Tablet)

Selinex is prescribed for adult patients with:

Multiple Myeloma

  • Relapsed or refractory disease

  • Used alone or in combination therapy

  • Helps induce cancer cell death

Diffuse Large B-Cell Lymphoma (DLBCL)

  • For patients with limited treatment options

  • Slows disease progression


How Selinex Works

Selinexor inhibits the export of tumor suppressor proteins from the nucleus.

Mechanism of Action

  • Blocks XPO1 protein activity

  • Retains tumor suppressor proteins in the nucleus

  • Triggers cancer cell apoptosis


Dosage and Administration

Dosage and treatment schedule must be determined by an oncologist.

Administration Guidelines

  • Taken orally as prescribed

  • May be taken with or without food

  • Often used in combination with other medicines

Do not change the dose or stop treatment without medical advice.


Possible Side Effects

Side effects vary between individuals and treatment regimens.

Common Side Effects

  • Nausea

  • Fatigue

  • Loss of appetite

  • Diarrhea

Less Common Side Effects

  • Low blood cell counts

  • Weight loss

  • Dizziness

Inform your doctor if side effects become severe or persistent.


Warnings and Precautions

Selinex should only be used under strict medical supervision.

Important Safety Information

  • Prescription-only oncology medicine

  • Regular blood tests may be required

  • Risk of dehydration and electrolyte imbalance

  • Inform your doctor of all medicines being taken


Storage Instructions

Proper Storage

  • Store below 30°C

  • Protect from moisture and light

  • Keep out of reach of children


Frequently Asked Questions

What is Selinex used for?

Selinex is used to treat multiple myeloma and diffuse large B-cell lymphoma in adults.

Is Selinex chemotherapy?

No. It is a targeted cancer therapy, not traditional chemotherapy.

Can Selinex be taken long term?

Yes, depending on response and tolerance, under oncologist supervision.

Does Selinex cure cancer?

It does not cure cancer but helps control disease progression.


Medical Disclaimer

This information is for educational purposes only and does not replace professional medical advice.

Product Categories

  • Oncology Medicines

  • Multiple Myeloma Treatment

  • Targeted Cancer Therapy

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