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Xeljanz (Tofacitinib) 5 mg– JAK Inhibitor for Psoriasis

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Xeljanz (Tofacitinib) 5 mg is an advanced oral JAK inhibitor designed to reduce inflammation and joint pain in adults with moderate to severe rheumatoid arthritis. Ideal for patients who do not respond to methotrexate. Fast relief, proven results, global availability.

Feature Details
Brand Xeljanz
Generic Brand Tofacent
Generic Name Tofacitinib
Class JAK1 / JAK3 Inhibitor
Strength 5 mg
Pack Size 60 Tablets
Dosage Form Tablet
Manufacturer Incepta Pharmaceuticals Ltd., Bangladesh
Uses Psoriasis, Vitiligo (off-label), Alopecia, Arthritis
Suitable For Inflammatory & Autoimmune Skin Diseases
Category JAK Inhibitor

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Xeljanz (Tofacitinib) 5 mg Tablets – 

Targeted JAK Inhibitor for Rheumatoid Arthritis


Product Overview of Xeljanz (Tofacitinib) 5 mg– JAK Inhibitor psoriasis

Xeljanz (Tofacitinib) 5 mg is an advanced oral Janus kinase (JAK) inhibitor used worldwide for managing moderately to severely active rheumatoid arthritis (RA). It helps reduce inflammation, alleviate joint pain, and improve mobility in patients who did not respond adequately to traditional DMARDs such as methotrexate.

Approved in major global markets, Xeljanz offers a convenient twice-daily oral therapy alternative to injectable biologics.


🔬 Key Features & Benefits

  • Targeted JAK inhibition for fast, effective immune modulation

  • Clinically proven to reduce RA symptoms and improve daily functioning

  • Oral tablet—no injections required

  • ✔ Can be used alone or with non-biologic DMARDs

  • ✔ Effective for patients unresponsive to methotrexate

  • ✔ Supports long-term control of inflammation and joint damage


🩺 Indications (Global)

Xeljanz / Tofacitinib 5 mg is commonly prescribed for:

Rheumatoid Arthritis (Primary Use)

  • Adults with moderately to severely active RA

  • Patients with inadequate response to methotrexate or other DMARDs

Additional worldwide-approved uses include:

  • Psoriatic arthritis

  • Ulcerative colitis (specific dosing differs)

  • Ankylosing spondylitis

(Indications vary by country. Always follow your local prescribing information.)


⚙️ How It Works

Tofacitinib selectively inhibits JAK1 and JAK3 pathways that regulate immune cell activity.
This reduces inflammatory cytokines responsible for:

  • joint swelling

  • stiffness

  • pain

  • long-term structural damage

The result is better mobility, reduced disease progression, and improved quality of life.


💊 Dosage & Administration

  • Standard RA dose: 5 mg twice daily

  • Can be taken with or without food

  • Swallow tablet whole

  • Dose adjustments may be required in renal/hepatic impairment

Your physician determines the most appropriate regimen.


⚠️ Safety Information

Common Side Effects

  • Headache

  • High cholesterol

  • Upper respiratory infections

  • Nausea or stomach discomfort

  • High blood pressure

Serious but less common risks

  • Severe infections

  • Blood clots (DVT/PE)

  • Cardiovascular events

  • Cancers (rare)

  • Liver enzyme elevation

Seek medical attention if you experience chest pain, breathing difficulty, persistent fever, or unusual bruising.


🔐 Precautions

  • Not recommended with biologic immunosuppressants

  • Screen for TB, hepatitis, and infections before initiation

  • Routine monitoring of CBC, liver function, kidney function, lipid levels

  • Avoid live vaccines during treatment

  • Use during pregnancy or breastfeeding only under medical supervision


🌡️ Storage

  • Store between 15°C – 30°C

  • Keep away from sunlight and moisture

  • Store out of reach of children


🛒 Why Customers Choose Xeljanz (Tofacitinib) 5 mg

  • Trusted globally by rheumatologists

  • Oral alternative to injectable RA biologics

  • Proven efficacy across diverse patient groups

  • Fast symptom relief and long-term disease control


FAQ 

1. What is Xeljanz used for?

Primarily for treating moderate to severe rheumatoid arthritis in adults.

2. How long does it take to work?

Many patients see improvement within 2–6 weeks.

3. Is Xeljanz better than injectable biologics?

It provides a convenient oral alternative and works well for many patients unresponsive to standard therapies.

4. Can I buy Xeljanz online internationally?

Yes, many global pharmacies and exporters provide worldwide shipping depending on regulatory laws.

5. Do I need a prescription?

Yes. It is a prescription-only medication in all global markets.

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